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Hemokinin-1 is a mediator of chronic restraint stress-induced pain

Hemokinin-1 is a mediator of chronic restraint stress-induced pain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e52d5aee3a544516987c691bffd30f12

Hemokinin-1 is a mediator of chronic restraint stress-induced pain

About this item

Full title

Hemokinin-1 is a mediator of chronic restraint stress-induced pain

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-11, Vol.13 (1), p.20030-20030, Article 20030

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The
Tac4
gene-derived hemokinin-1 (HK-1) binds to the NK1 receptor, similarly to Substance P, and plays a role in acute stress reactions and pain transmission in mice. Here we investigated Tac4 mRNA expression in stress and pain-related regions and its involvement in chronic restraint stress-evoked behavioral changes and pain using
Tac4

Alternative Titles

Full title

Hemokinin-1 is a mediator of chronic restraint stress-induced pain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e52d5aee3a544516987c691bffd30f12

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e52d5aee3a544516987c691bffd30f12

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-46402-7

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