Structural Analysis of the cl-Par-4 Tumor Suppressor as a Function of Ionic Environment
Structural Analysis of the cl-Par-4 Tumor Suppressor as a Function of Ionic Environment
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Prostate apoptosis response-4 (Par-4) is a proapoptotic tumor suppressor protein that has been linked to a large number of cancers. This 38 kilodalton (kDa) protein has been shown to be predominantly intrinsically disordered in vitro. In vivo, Par-4 is cleaved by caspase-3 at Asp-131 to generate the 25 kDa functionally active cleaved Par-4 protein...
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Full title
Structural Analysis of the cl-Par-4 Tumor Suppressor as a Function of Ionic Environment
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TN_cdi_doaj_primary_oai_doaj_org_article_e53cae6fed574674856bf4186be217f5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e53cae6fed574674856bf4186be217f5
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom11030386
