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Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5533df521cf4e0dbcafe95d43d2021b

Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

About this item

Full title

Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2021-12, Vol.14 (12)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Fundamental questions about patient heterogeneity and human-specific pathophysiology currently obstruct progress towards a therapy for traumatic brain injury (TBI). Human in vitro models have the potential to address these questions. Three-dimensional spheroidal cell culture protocols for human-origin neural cells have several important advantages...

Alternative Titles

Full title

Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e5533df521cf4e0dbcafe95d43d2021b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5533df521cf4e0dbcafe95d43d2021b

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.048916

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