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Acetoacetate, a ketone body, attenuates neuronal bursts in acutely-induced epileptiform slices of th...

Acetoacetate, a ketone body, attenuates neuronal bursts in acutely-induced epileptiform slices of th...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e58d79371e1c4205a3f350cc122c8cb0

Acetoacetate, a ketone body, attenuates neuronal bursts in acutely-induced epileptiform slices of the mouse hippocampus

About this item

Full title

Acetoacetate, a ketone body, attenuates neuronal bursts in acutely-induced epileptiform slices of the mouse hippocampus

Publisher

Switzerland: Frontiers Research Foundation

Journal title

Frontiers in cellular neuroscience, 2025-03, Vol.19, p.1551700

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Research Foundation

More information

Scope and Contents

Contents

The ketogenic diet increases ketone bodies (β-hydroxybutyrate and acetoacetate) in the brain, and ameliorates epileptic seizures in vivo . However, ketone bodies exert weak or no effects on electrical activity in rodent hippocampal slices. Especially, it remains unclear what kinds of conditions are required to strengthen the actions of ketone bodie...

Alternative Titles

Full title

Acetoacetate, a ketone body, attenuates neuronal bursts in acutely-induced epileptiform slices of the mouse hippocampus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e58d79371e1c4205a3f350cc122c8cb0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e58d79371e1c4205a3f350cc122c8cb0

Other Identifiers

ISSN

1662-5102

E-ISSN

1662-5102

DOI

10.3389/fncel.2025.1551700

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