Cannabidiol activates neuronal Kv7 channels
Cannabidiol activates neuronal Kv7 channels
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Cannabidiol (CBD), a chemical found in the
Cannabis sativa
plant, is a clinically effective antiepileptic drug whose mechanism of action is unknown. Using a fluorescence-based thallium flux assay, we performed a large-scale screen and found enhancement of flux through heterologously expressed human Kv7.2/7.3 channels by CBD. Patch-clamp recor...
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Full title
Cannabidiol activates neuronal Kv7 channels
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TN_cdi_doaj_primary_oai_doaj_org_article_e58eafd704e84f2b9bdbc4303277ac23
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e58eafd704e84f2b9bdbc4303277ac23
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.73246
