YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution
YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution
About this item
Full title
Author / Creator
Faraji, Farhoud , Ramirez, Sydney I. , Clubb, Lauren M. , Sato, Kuniaki , Burghi, Valeria , Hoang, Thomas S. , Officer, Adam , Anguiano Quiroz, Paola Y. , Galloway, William M. G. , Mikulski, Zbigniew , Medetgul-Ernar, Kate , Marangoni, Pauline , Jones, Kyle B. , Cao, Yuwei , Molinolo, Alfredo A. , Kim, Kenneth , Sakaguchi, Kanako , Califano, Joseph A. , Smith, Quinton , Goren, Alon , Klein, Ophir D. , Tamayo, Pablo and Gutkind, J. Silvio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tumor initiation represents the first step in tumorigenesis during which normal progenitor cells undergo cell fate transition to cancer. Capturing this process as it occurs in vivo, however, remains elusive. Here we employ spatiotemporally controlled oncogene activation and tumor suppressor inhibition together with multiomics to unveil the processe...
Alternative Titles
Full title
YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution
Authors, Artists and Contributors
Author / Creator
Ramirez, Sydney I.
Clubb, Lauren M.
Sato, Kuniaki
Burghi, Valeria
Hoang, Thomas S.
Officer, Adam
Anguiano Quiroz, Paola Y.
Galloway, William M. G.
Mikulski, Zbigniew
Medetgul-Ernar, Kate
Marangoni, Pauline
Jones, Kyle B.
Cao, Yuwei
Molinolo, Alfredo A.
Kim, Kenneth
Sakaguchi, Kanako
Califano, Joseph A.
Smith, Quinton
Goren, Alon
Klein, Ophir D.
Tamayo, Pablo
Gutkind, J. Silvio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e5971d932e7d400298d4ef57b0c8c908
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5971d932e7d400298d4ef57b0c8c908
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55660-6
