Induction of amyloid-β deposits from serially transmitted, histologically silent, Aβ seeds issued fr...
Induction of amyloid-β deposits from serially transmitted, histologically silent, Aβ seeds issued from human brains
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
In humans, iatrogenic transmission of cerebral amyloid-β (Aβ)-amyloidosis is suspected following inoculation of pituitary-derived hormones or dural grafts presumably contaminated with Aβ proteins as well as after cerebral surgeries. Experimentally, intracerebral inoculation of brain homogenate extracts containing misfolded Aβ can seed Aβ deposition...
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Full title
Induction of amyloid-β deposits from serially transmitted, histologically silent, Aβ seeds issued from human brains
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TN_cdi_doaj_primary_oai_doaj_org_article_e5c5d8960af64e8e93784c6732f96349
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5c5d8960af64e8e93784c6732f96349
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-020-01081-7
