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Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5cc6bbdb30641829f5b58b0a8df2eaf

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

About this item

Full title

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-12, Vol.10 (1), p.5816-17, Article 5816

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Microglia survey brain parenchyma, responding to injury and infections. Microglia also respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this process remains unclear. Using simultaneous in vivo imaging, we demonstrated that systemic inflammation induces CCR5-dependent migration of brain resident microglia to the ce...

Alternative Titles

Full title

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e5cc6bbdb30641829f5b58b0a8df2eaf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e5cc6bbdb30641829f5b58b0a8df2eaf

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13812-z

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