Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and asso...
Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease
About this item
Full title
Author / Creator
Williams, Alexander T. , Chen, Jing , Coley, Kayesha , Batini, Chiara , Izquierdo, Abril , Packer, Richard , Abner, Erik , Kanoni, Stavroula , Shepherd, David J. , Free, Robert C. , Hollox, Edward J. , Brunskill, Nigel J. , Ntalla, Ioanna , Reeve, Nicola , Brightling, Christopher E. , Venn, Laura , Adams, Emma , Bee, Catherine , Wallace, Susan E. , Pareek, Manish , Hansell, Anna L. , Esko, Tõnu , Stow, Daniel , Jacobs, Benjamin M. , van Heel, David A. , Hennah, William , Rao, Balasubramanya S. , Dudbridge, Frank , Wain, Louise V. , Shrine, Nick , Tobin, Martin D. , John, Catherine , Estonian Biobank Research Team and Genes & Health Research Team
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Thyroid hormones play a critical role in regulation of multiple physiological functions and thyroid dysfunction is associated with substantial morbidity. Here, we use electronic health records to undertake a genome-wide association study of thyroid-stimulating hormone (TSH) levels, with a total sample size of 247,107. We identify 158 novel genetic...
Alternative Titles
Full title
Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease
Authors, Artists and Contributors
Author / Creator
Chen, Jing
Coley, Kayesha
Batini, Chiara
Izquierdo, Abril
Packer, Richard
Abner, Erik
Kanoni, Stavroula
Shepherd, David J.
Free, Robert C.
Hollox, Edward J.
Brunskill, Nigel J.
Ntalla, Ioanna
Reeve, Nicola
Brightling, Christopher E.
Venn, Laura
Adams, Emma
Bee, Catherine
Wallace, Susan E.
Pareek, Manish
Hansell, Anna L.
Esko, Tõnu
Stow, Daniel
Jacobs, Benjamin M.
van Heel, David A.
Hennah, William
Rao, Balasubramanya S.
Dudbridge, Frank
Wain, Louise V.
Shrine, Nick
Tobin, Martin D.
John, Catherine
Estonian Biobank Research Team
Genes & Health Research Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e621fa13197b48d594bb390c78b9b2c1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e621fa13197b48d594bb390c78b9b2c1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42284-5
