Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertil...
Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Following fertilization, cortical granules exocytose ovastacin, a metalloendopeptidase that cleaves ZP2 in the zona pellucida surrounding mouse eggs to prevent additional sperm binding. Using high- and super-resolution imaging with ovastacin
mCherry
as a fluorescent marker, we characterize cortical granule dynamics at single granule resolutio...
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Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis
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TN_cdi_doaj_primary_oai_doaj_org_article_e6424900b9c54c2f9956c43155b7d5da
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6424900b9c54c2f9956c43155b7d5da
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10171-7
