Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nu...
Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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This study presents a novel approach for mapping global chromatin interactions using S1 nuclease, a sequence-agnostic enzyme. We develop and outline a protocol that leverages S1 nuclease's ability to effectively introduce breaks into both open and closed chromatin regions, allowing for comprehensive profiling of chromatin properties. Our S1 Hi–C me...
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Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease
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TN_cdi_doaj_primary_oai_doaj_org_article_e64f909007a14bb88f42f13fbe48507a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e64f909007a14bb88f42f13fbe48507a
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ISSN
1756-8935
E-ISSN
1756-8935
DOI
10.1186/s13072-023-00524-4