Interplay between human STING genotype and bacterial NADase activity regulates inter-individual dise...
Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability
About this item
Full title
Author / Creator
Movert, Elin , Bolarin, Jaume Salgado , Valfridsson, Christine , Velarde, Jorge , Skrede, Steinar , Nekludov, Michael , Hyldegaard, Ole , Arnell, Per , Svensson, Mattias , Norrby-Teglund, Anna , Cho, Kyu Hong , Elhaik, Eran , Wessels, Michael R. , Råberg, Lars , Carlsson, Fredric , Naturvetenskapliga fakulteten , Lund University , Bioinformatics , Biologiska institutionen , Mikrobiologigruppen , Forskargrupper vid Biologiska institutionen , Department of Biology , Research groups at the Department of Biology , Bioinformatik , Faculty of Science , Lunds universitet and Microbiology Group
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Variability in disease severity caused by a microbial pathogen is impacted by each infection representing a unique combination of host and pathogen genomes. Here, we show that the outcome of invasive
Streptococcus pyogenes
infection is regulated by an interplay between human STING genotype and bacterial NADase activity.
S. pyogenes
-der...
Alternative Titles
Full title
Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability
Authors, Artists and Contributors
Author / Creator
Bolarin, Jaume Salgado
Valfridsson, Christine
Velarde, Jorge
Skrede, Steinar
Nekludov, Michael
Hyldegaard, Ole
Arnell, Per
Svensson, Mattias
Norrby-Teglund, Anna
Cho, Kyu Hong
Elhaik, Eran
Wessels, Michael R.
Råberg, Lars
Carlsson, Fredric
Naturvetenskapliga fakulteten
Lund University
Bioinformatics
Biologiska institutionen
Mikrobiologigruppen
Forskargrupper vid Biologiska institutionen
Department of Biology
Research groups at the Department of Biology
Bioinformatik
Faculty of Science
Lunds universitet
Microbiology Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e6892bfbcad24fc4a8d136c2cda1ce1b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6892bfbcad24fc4a8d136c2cda1ce1b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39771-0
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