Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis
Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Blood transfusion plays a vital role in modern medicine, but frequent shortages occur. Ex vivo manufacturing of red blood cells (RBCs) from universal donor cells offers a potential solution, yet the high cost of recombinant cytokines remains a barrier. Erythropoietin (EPO) signaling is crucial for RBC development, and EPO is among the most expensiv...
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Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis
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TN_cdi_doaj_primary_oai_doaj_org_article_e697085028b54932a61c99c01da9de10
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e697085028b54932a61c99c01da9de10
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56239-5
