Effects of the Combination of the C1473G Mutation in the Tph2 Gene and Lethal Yellow Mutations in th...
Effects of the Combination of the C1473G Mutation in the Tph2 Gene and Lethal Yellow Mutations in the Raly-Agouti Locus on Behavior, Brain 5-HT and Melanocortin Systems in Mice
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Tryptophan hydroxylase 2 (TPH2) is the key and rate-limited enzyme of serotonin (5-HT) synthesis in the brain. The C1473G mutation in the Tph2 gene results in a two-fold decrease in enzyme activity in the mouse brain. The lethal yellow (AY) mutation in the Raly-Agouti locus results in the overexpression of the Agouti gene in the brain and causes ob...
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Full title
Effects of the Combination of the C1473G Mutation in the Tph2 Gene and Lethal Yellow Mutations in the Raly-Agouti Locus on Behavior, Brain 5-HT and Melanocortin Systems in Mice
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TN_cdi_doaj_primary_oai_doaj_org_article_e69afe9657704615a79ec0264f8e17a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e69afe9657704615a79ec0264f8e17a8
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom13060963
