Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
About this item
Full title
Author / Creator
Mata, Douglas A. , Benhamida, Jamal K. , Lin, Andrew L. , Vanderbilt, Chad M. , Yang, Soo-Ryum , Villafania, Liliana B. , Ferguson, Donna C. , Jonsson, Philip , Miller, Alexandra M. , Tabar, Viviane , Brennan, Cameron W. , Moss, Nelson S. , Sill, Martin , Benayed, Ryma , Mellinghoff, Ingo K. , Rosenblum, Marc K. , Arcila, Maria E. , Ladanyi, Marc and Bale, Tejus A.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic
FGFR3
-
TACC3
(F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency of F3T3-fusion positivity, its associated genetic and methylation profiles, and its impact on survival in 906 IDH-wildtype G...
Alternative Titles
Full title
Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
Authors, Artists and Contributors
Author / Creator
Benhamida, Jamal K.
Lin, Andrew L.
Vanderbilt, Chad M.
Yang, Soo-Ryum
Villafania, Liliana B.
Ferguson, Donna C.
Jonsson, Philip
Miller, Alexandra M.
Tabar, Viviane
Brennan, Cameron W.
Moss, Nelson S.
Sill, Martin
Benayed, Ryma
Mellinghoff, Ingo K.
Rosenblum, Marc K.
Arcila, Maria E.
Ladanyi, Marc
Bale, Tejus A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e6a9da3b0b01489295be630dcbaceb95
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6a9da3b0b01489295be630dcbaceb95
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-020-01058-6
