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Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient ex...

Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient ex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6b05651e57b4624a0657c2b371e719f

Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature

About this item

Full title

Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature

Publisher

England: BioMed Central Ltd

Journal title

Journal of medical case reports, 2009-09, Vol.3 (1), p.9132-9132

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Selection of the K103N mutation is associated with moderately reduced in vitro fitness of HIV. Strains bearing K103N in vivo tend to persist, even in the absence of additional drug pressure, as minority quasispecies, often undetectable in genotyping resistance testing assays, performed at standard conditions. Here, we report on the rapid and long l...

Alternative Titles

Full title

Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e6b05651e57b4624a0657c2b371e719f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6b05651e57b4624a0657c2b371e719f

Other Identifiers

ISSN

1752-1947

E-ISSN

1752-1947

DOI

10.4076/1752-1947-3-9132

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