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Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxo...

Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6bae727d3b348d2a15b6c1b9e0e6d04

Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin

About this item

Full title

Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin

Publisher

Poland: BioMed Central Ltd

Journal title

Hereditary cancer in clinical practice, 2021-02, Vol.19 (1), p.14-14, Article 14

Language

English

Formats

Publication information

Publisher

Poland: BioMed Central Ltd

More information

Scope and Contents

Contents

Cisplatin, mitomycin C and anthracyclines demonstrate high activity in BRCA1-deficient tumors. This study aimed to evaluate the efficacy of the triplet combination of these drugs in BRCA1-driven high-grade serous ovarian carcinomas (HGSOCs).
Ten HGSOC patients with germ-line BRCA1 mutation received neoadjuvant chemotherapy (NACT) consisting of m...

Alternative Titles

Full title

Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e6bae727d3b348d2a15b6c1b9e0e6d04

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e6bae727d3b348d2a15b6c1b9e0e6d04

Other Identifiers

ISSN

1897-4287,1731-2302

E-ISSN

1897-4287

DOI

10.1186/s13053-021-00173-2

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