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snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives

snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e72696809e1b4d6fbd26435761d09282

snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Formalin-fixed paraffin-embedded (FFPE) samples are valuable but underutilized in single-cell omics research due to their low RNA quality. In this study, leveraging a recent advance in single-cell genomic technology, we introduce snPATHO-seq, a versatile method to derive high-quality single-nucleus transcriptomic data from FFPE samples. We benchmar...

Alternative Titles

Full title

snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e72696809e1b4d6fbd26435761d09282

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e72696809e1b4d6fbd26435761d09282

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-024-07043-2

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