Cyclical regression covariates remove the major confounding effect of cyclical developmental gene ex...
Cyclical regression covariates remove the major confounding effect of cyclical developmental gene expression with strain-specific drug response in the malaria parasite Plasmodium falciparum
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Publisher
England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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The cyclical nature of gene expression in the intraerythrocytic development cycle (IDC) of the malaria parasite, Plasmodium falciparum, confounds the accurate detection of specific transcriptional differences, e.g. as provoked by the development of drug resistance. In lab-based studies, P. falciparum cultures are synchronized to remove this confoun...
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Full title
Cyclical regression covariates remove the major confounding effect of cyclical developmental gene expression with strain-specific drug response in the malaria parasite Plasmodium falciparum
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TN_cdi_doaj_primary_oai_doaj_org_article_e734eadf127246e68b31b23d33ac8bf4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e734eadf127246e68b31b23d33ac8bf4
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-021-08281-y
