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A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7387f8418fd4439a8a668e9564cc12b

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

About this item

Full title

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-08, Vol.10 (1), p.3660-16, Article 3660

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Virtually all tumors are genetically heterogeneous, containing mutationally-defined subclonal cell populations that often have distinct phenotypes. Single-cell RNA-sequencing has revealed that a variety of tumors are also transcriptionally heterogeneous, but the relationship between expression heterogeneity and subclonal architecture is unclear. He...

Alternative Titles

Full title

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e7387f8418fd4439a8a668e9564cc12b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7387f8418fd4439a8a668e9564cc12b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-11591-1

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