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Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainag...

Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainag...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e73bbbf27a75479ab52ad1b58a25589a

Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainage pathways

About this item

Full title

Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainage pathways

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-11, Vol.14 (1), p.27982-13, Article 27982

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The aquaporin-4 (AQP4) water channel is essential in neurofluid dynamics. AQP4 loss impairs solute exchange between the cerebrospinal fluid (CSF) and interstitial fluid (ISF). However, whether AQP4 expression affects solute clearance from the CSF space to the extracranial space remains unclear. This study aimed to investigate this using dynamic con...

Alternative Titles

Full title

Loss of aquaporin-4 impairs cerebrospinal fluid solute clearance through cerebrospinal fluid drainage pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e73bbbf27a75479ab52ad1b58a25589a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e73bbbf27a75479ab52ad1b58a25589a

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-79147-y

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