Two simple assays for assessing the seeding activity of proteopathic tau
Two simple assays for assessing the seeding activity of proteopathic tau
About this item
Full title
Author / Creator
Liu, Fei , Wu, Ruozhen , Jin, Nana , Chu, Dandan , Gu, Jianlan , Tung, Yunn Chyn , Hu, Zhihao , Gong, Cheng-Xin and Iqbal, Khalid
Publisher
Switzerland: Frontiers Media S.A
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: Frontiers Media S.A
Subjects
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Scope and Contents
Contents
The regional distribution of neurofibrillary tangles of hyperphosphorylated tau aggregates is associated with the progression of Alzheimer’s disease (AD). Misfolded proteopathic tau recruits naïve tau and templates its misfolding and aggregation in a prion-like fashion, which is believed to be the molecular basis of propagation of tau pathology. A...
Alternative Titles
Full title
Two simple assays for assessing the seeding activity of proteopathic tau
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e752612289d7476dafaf56c7e75bd1a0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e752612289d7476dafaf56c7e75bd1a0
Other Identifiers
ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2023.1073774
