A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signa...
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways
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Author / Creator
Pattwell, Siobhan S. , Arora, Sonali , Cimino, Patrick J. , Ozawa, Tatsuya , Szulzewsky, Frank , Hoellerbauer, Pia , Bonifert, Tobias , Hoffstrom, Benjamin G. , Boiani, Norman E. , Bolouri, Hamid , Correnti, Colin E. , Oldrini, Barbara , Silber, John R. , Squatrito, Massimo , Paddison, Patrick J. and Holland, Eric C.
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Independent scientific achievements have led to the discovery of aberrant splicing patterns in oncogenesis, while more recent advances have uncovered novel gene fusions involving neurotrophic tyrosine receptor kinases (NTRKs) in gliomas. The exploration of
NTRK
splice variants in normal and neoplastic brain provides an intersection of these t...
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A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways
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TN_cdi_doaj_primary_oai_doaj_org_article_e76b737ec4c34d949cb32dc9395b4f44
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e76b737ec4c34d949cb32dc9395b4f44
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16786-5
