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Combining Asian and European genome-wide association studies of colorectal cancer improves risk pred...

Combining Asian and European genome-wide association studies of colorectal cancer improves risk pred...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7a280372db24e62a96e2b247dd52766

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

About this item

Full title

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Author / Creator

Thomas, Minta , Su, Yu-Ru , Sakoda, Lori C. , Schmit, Stephanie L. , Timofeeva, Maria N. , Chen, Zhishan , Fernandez-Rozadilla, Ceres , Law, Philip J. , Murphy, Neil , Carreras-Torres, Robert , van Duijnhoven, Franzel J. B. , Shin, Aesun , Wolk, Alicja , Phipps, Amanda I. , Zauber, Ann G. , Wu, Anna H. , Um, Caroline Y. , Tangen, Catherine M. , Gignoux, Chris , Newton, Christina , Haiman, Christopher A. , Qu, Conghui , Bishop, D. Timothy , Buchanan, Daniel D. , Crosslin, David R. , Kim, Dong-Hyun , Hauser, Elizabeth , White, Emily , Siegel, Erin , Rennert, Gad , Giles, Graham G. , Hampel, Heather , Brenner, Hermann , Oze, Isao , Lee, Jeffrey K. , Kim, Jeongseon , Huyghe, Jeroen R. , Zheng, Jiayin , Hampe, Jochen , Greenson, Joel , Palmer, Julie R. , Visvanathan, Kala , Matsuo, Keitaro , Jung, Keum Ji , Li, Li , Le Marchand, Loic , Vodickova, Ludmila , Bujanda, Luis , Matejcic, Marco , Jenkins, Mark A. , Slattery, Martha L. , D’Amato, Mauro , Hoffmeister, Michael , Woods, Michael O. , Kim, Michelle , Song, Mingyang , Iwasaki, Motoki , Du, Mulong , Sawada, Norie , Vodicka, Pavel , Campbell, Peter T. , Pearlman, Rachel , Pai, Rish K. , Prentice, Ross L. , Küry, Sébastien , Castellví-Bel, Sergi , Berndt, Sonja I. , Lee, Soo Chin , Brezina, Stefanie , Weinstein, Stephanie J. , Chanock, Stephen J. , Jee, Sun Ha , Kweon, Sun-Seog , Vadaparampil, Susan , Harrison, Tabitha A. , Yamaji, Taiki , Keku, Temitope O. , Vymetalkova, Veronika , Arndt, Volker , Jia, Wei-Hua , Shu, Xiao-Ou , Lin, Yi , Ahn, Yoon-Ok , Stadler, Zsofia K. , Van Guelpen, Bethany , Ulrich, Cornelia M. , Li, Christopher I. , Meester, Reinier , Moreno, Victor , Figueiredo, Jane C. , Casey, Graham , Lansdorp Vogelaar, Iris , Dunlop, Malcolm G. , Hayes, Richard B. , Pharoah, Paul D. P. , Houlston, Richard S. , Jarvik, Gail P. , Tomlinson, Ian P. , Zheng, Wei and Corley, Douglas A.

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-10, Vol.14 (1), p.6147-13, Article 6147

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry data have sub-optimal performance in non-European ancestry populations, limiting their utility among these populations. Towards addre...

Alternative Titles

Full title

Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations

Authors, Artists and Contributors

Author / Creator

Thomas, Minta
Su, Yu-Ru
Sakoda, Lori C.
Schmit, Stephanie L.
Timofeeva, Maria N.
Chen, Zhishan
Fernandez-Rozadilla, Ceres
Law, Philip J.
Murphy, Neil
Carreras-Torres, Robert
van Duijnhoven, Franzel J. B.
Shin, Aesun
Wolk, Alicja
Phipps, Amanda I.
Zauber, Ann G.
Wu, Anna H.
Um, Caroline Y.
Tangen, Catherine M.
Gignoux, Chris
Newton, Christina
Haiman, Christopher A.
Qu, Conghui
Bishop, D. Timothy
Buchanan, Daniel D.
Crosslin, David R.
Kim, Dong-Hyun
Hauser, Elizabeth
White, Emily
Siegel, Erin
Rennert, Gad
Giles, Graham G.
Hampel, Heather
Brenner, Hermann
Oze, Isao
Lee, Jeffrey K.
Kim, Jeongseon
Huyghe, Jeroen R.
Zheng, Jiayin
Hampe, Jochen
Greenson, Joel
Palmer, Julie R.
Visvanathan, Kala
Matsuo, Keitaro
Jung, Keum Ji
Li, Li
Le Marchand, Loic
Vodickova, Ludmila
Bujanda, Luis
Matejcic, Marco
Jenkins, Mark A.
Slattery, Martha L.
D’Amato, Mauro
Hoffmeister, Michael
Woods, Michael O.
Kim, Michelle
Song, Mingyang
Iwasaki, Motoki
Du, Mulong
Sawada, Norie
Vodicka, Pavel
Campbell, Peter T.
Pearlman, Rachel
Pai, Rish K.
Prentice, Ross L.
Küry, Sébastien
Castellví-Bel, Sergi
Berndt, Sonja I.
Lee, Soo Chin
Brezina, Stefanie
Weinstein, Stephanie J.
Chanock, Stephen J.
Jee, Sun Ha
Kweon, Sun-Seog
Vadaparampil, Susan
Harrison, Tabitha A.
Yamaji, Taiki
Keku, Temitope O.
Vymetalkova, Veronika
Arndt, Volker
Jia, Wei-Hua
Shu, Xiao-Ou
Lin, Yi
Ahn, Yoon-Ok
Stadler, Zsofia K.
Van Guelpen, Bethany
Ulrich, Cornelia M.
Li, Christopher I.
Meester, Reinier
Moreno, Victor
Figueiredo, Jane C.
Casey, Graham
Lansdorp Vogelaar, Iris
Dunlop, Malcolm G.
Hayes, Richard B.
Pharoah, Paul D. P.
Houlston, Richard S.
Jarvik, Gail P.
Tomlinson, Ian P.
Zheng, Wei
Corley, Douglas A.

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e7a280372db24e62a96e2b247dd52766

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7a280372db24e62a96e2b247dd52766

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-41819-0

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