FGF21 modulates immunometabolic homeostasis via the ALOX15/15-HETE axis in early liver graft injury
FGF21 modulates immunometabolic homeostasis via the ALOX15/15-HETE axis in early liver graft injury
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Author / Creator
Yang, Xinyu , Chen, Hao , Shen, Wei , Chen, Yuanming , Lin, Zuyuan , Zhuo, Jianyong , Wang, Shuai , Yang, Modan , Li, Huigang , He, Chiyu , Zhang, Xuanyu , Hu, Zhihang , Lian, Zhengxing , Yang, Mengfan , Wang, Rui , Li, Changbiao , Pan, Binhua , Xu, Li , Chen, Jun , Wei, Xuyong , Wei, Qiang , Xie, Haiyang , Zheng, Shusen , Lu, Di and Xu, Xiao
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Fibroblast growth factor 21 (FGF21) is essential for modulating hepatic homeostasis, but the impact of FGF21 on liver graft injury remains uncertain. Here, we show that high FGF21 levels in liver graft and serum are associated with improved graft function and survival in liver transplantation (LT) recipients. FGF21 deficiency aggravates early graft...
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FGF21 modulates immunometabolic homeostasis via the ALOX15/15-HETE axis in early liver graft injury
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TN_cdi_doaj_primary_oai_doaj_org_article_e7c144a39ae440d2a16acc94b96c3e6b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7c144a39ae440d2a16acc94b96c3e6b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52379-2
