Synthesis, Docking, and DFT Studies on Novel Schiff Base Sulfonamide Analogues as Selective COX-1 In...
Synthesis, Docking, and DFT Studies on Novel Schiff Base Sulfonamide Analogues as Selective COX-1 Inhibitors with Anti-Platelet Aggregation Activity
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Selective COX-1 inhibitors are preferential therapeutic targets for platelet aggregation and clotting responses. In this study, we examined the selective COX-1-inhibitory activities of four newly synthesized compounds,
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, along with their abilities to inhibit platelet aggregation against ADP and collagen. The target compounds
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were sy...
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Full title
Synthesis, Docking, and DFT Studies on Novel Schiff Base Sulfonamide Analogues as Selective COX-1 Inhibitors with Anti-Platelet Aggregation Activity
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TN_cdi_doaj_primary_oai_doaj_org_article_e7e43df42e6b4425990dfbd765b445b0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7e43df42e6b4425990dfbd765b445b0
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph17060710
