Protocatechuic acid attenuates isoproterenol-induced cardiac hypertrophy via downregulation of ROCK1...
Protocatechuic acid attenuates isoproterenol-induced cardiac hypertrophy via downregulation of ROCK1–Sp1–PKCγ axis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cardiac hypertrophy is an adaptive response of the myocardium to pressure overload or adrenergic agonists. Here, we investigated the protective effects and the regulatory mechanism of protocatechuic acid, a phenolic compound, using a mouse model of isoproterenol-induced cardiac hypertrophy. Our results demonstrated that protocatechuic acid treatmen...
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Protocatechuic acid attenuates isoproterenol-induced cardiac hypertrophy via downregulation of ROCK1–Sp1–PKCγ axis
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TN_cdi_doaj_primary_oai_doaj_org_article_e7e466f0707c4b9c8bf4b22aa5842b2d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e7e466f0707c4b9c8bf4b22aa5842b2d
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-96761-2
