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Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e80facbfd7b94762a3e41e78b109cc7d

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

About this item

Full title

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-08, Vol.9 (1), p.3287-17, Article 3287

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Leukocytes are coated with a layer of heterogeneous carbohydrates (glycans) that modulate immune function, in part by governing specific interactions with glycan-binding proteins (lectins). Although nearly all membrane proteins bear glycans, the identity and function of most of these sugars on leukocytes remain unexplored. Here, we characterize the...

Alternative Titles

Full title

Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e80facbfd7b94762a3e41e78b109cc7d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e80facbfd7b94762a3e41e78b109cc7d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-05770-9

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