Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals
Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals
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Author / Creator
Vavoulis, Dimitrios V. , Cutts, Anthony , Thota, Nishita , Brown, Jordan , Sugar, Robert , Rueda, Antonio , Ardalan, Arman , Howard, Kieran , Matos Santo, Flavia , Sannasiddappa, Thippesh , Miller, Bronwen , Ash, Stephen , Liu, Yibin , Song, Chun-Xiao , Nicholson, Brian D. , Dreau, Helene , Tregidgo, Carolyn and Schuh, Anna
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The analysis of circulating tumour DNA (ctDNA) through minimally invasive liquid biopsies is promising for early multi-cancer detection and monitoring minimal residual disease. Most existing methods focus on targeted deep sequencing, but few integrate multiple data modalities. Here, we develop a methodology for ctDNA detection using deep (80x) whol...
Alternative Titles
Full title
Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e8180916444c4ebb9b244db737260b88
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8180916444c4ebb9b244db737260b88
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55428-y
