P2X Receptor-Dependent Erythrocyte Damage by α-Hemolysin from Escherichia coli Triggers Phagocytosis...
P2X Receptor-Dependent Erythrocyte Damage by α-Hemolysin from Escherichia coli Triggers Phagocytosis by THP-1 Cells
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Switzerland: MDPI
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English
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Switzerland: MDPI
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The pore-forming exotoxin α-hemolysin from E. coli causes a significant volume reduction of human erythrocytes that precedes the ultimate swelling and lysis. This shrinkage results from activation of Ca2+-sensitive K+ (KCa3.1) and Cl− channels (TMEM16A) and reduced functions of either of these channels potentiate the HlyA-induced hemolysis. This me...
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Full title
P2X Receptor-Dependent Erythrocyte Damage by α-Hemolysin from Escherichia coli Triggers Phagocytosis by THP-1 Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_e82f5523ff8f466f8f9e900bcb8b111e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e82f5523ff8f466f8f9e900bcb8b111e
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins5030472
