Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and...
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure
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Full title
Author / Creator
Hollestein, Viola , Poelmans, Geert , Forde, Natalie J. , Beckmann, Christian F. , Ecker, Christine , Mann, Caroline , Schäfer, Tim , Moessnang, Carolin , Baumeister, Sarah , Banaschewski, Tobias , Bourgeron, Thomas , Loth, Eva , Dell’Acqua, Flavio , Murphy, Declan G. M. , Puts, Nicolaas A. , Tillmann, Julian , Charman, Tony , Jones, Emily J. H. , Mason, Luke , Ambrosino, Sara , Holt, Rosemary , Bölte, Sven , Buitelaar, Jan K. and Naaijen, Jilly
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The excitatory/inhibitory (E/I) imbalance hypothesis posits that imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) mechanisms underlies the behavioral characteristics of autism. However, how E/I imbalance arises and how it may differ across autism symptomatology and brain regions is not well understood. We used innovative anal...
Alternative Titles
Full title
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure
Authors, Artists and Contributors
Author / Creator
Poelmans, Geert
Forde, Natalie J.
Beckmann, Christian F.
Ecker, Christine
Mann, Caroline
Schäfer, Tim
Moessnang, Carolin
Baumeister, Sarah
Banaschewski, Tobias
Bourgeron, Thomas
Loth, Eva
Dell’Acqua, Flavio
Murphy, Declan G. M.
Puts, Nicolaas A.
Tillmann, Julian
Charman, Tony
Jones, Emily J. H.
Mason, Luke
Ambrosino, Sara
Holt, Rosemary
Bölte, Sven
Buitelaar, Jan K.
Naaijen, Jilly
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e83023aeeeab4df09a5c4172ff9204e6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e83023aeeeab4df09a5c4172ff9204e6
Other Identifiers
ISSN
2158-3188
E-ISSN
2158-3188
DOI
10.1038/s41398-023-02317-5
