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Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strai...

Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strai...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e834b0f155bd43189596591d8f8a3953

Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains

About this item

Full title

Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2021-02, Vol.21 (1), p.172-10, Article 172

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Colibactin is a genotoxin that induces DNA double-strand breaks that may lead to carcinogenesis and is produced by Escherichia coli strains harboring the pks island. Human and animal studies have shown that colibactin-producing gut bacteria promote carcinogenesis and enhance the progression of colorectal cancer through cellular senescence and chrom...

Alternative Titles

Full title

Oligosaccharides increase the genotoxic effect of colibactin produced by pks+ Escherichia coli strains

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e834b0f155bd43189596591d8f8a3953

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e834b0f155bd43189596591d8f8a3953

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-021-07876-8

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