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Cell-intrinsic ceramides determine T cell function during melanoma progression

Cell-intrinsic ceramides determine T cell function during melanoma progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8451a73e0d644448fa86305cbe73999

Cell-intrinsic ceramides determine T cell function during melanoma progression

About this item

Full title

Cell-intrinsic ceramides determine T cell function during melanoma progression

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2022-11, Vol.11

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac. Ceramide generates ceramide-enriched platforms that are involved in receptor clustering within cellular membranes. However, the impact of cell-intrinsic ceramide...

Alternative Titles

Full title

Cell-intrinsic ceramides determine T cell function during melanoma progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e8451a73e0d644448fa86305cbe73999

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8451a73e0d644448fa86305cbe73999

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.83073

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