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Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e87abd4dde1941e494b09a4999a769d0

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2

About this item

Full title

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2

Publisher

Beijing: Higher Education Press

Journal title

Protein & cell, 2020-07, Vol.11 (7), p.505-517

Language

English

Formats

Publication information

Publisher

Beijing: Higher Education Press

More information

Scope and Contents

Contents

Inhibition of
Mycobacterium tuberculosis (Mtb)
cell wall assembly is an established strategy for anti-TB chemotherapy. Arabinosyltransferase EmbB, which catalyzes the transfer of arabinose from the donor decaprenyl-phosphate-arabinose (DPA) to its arabinosyl acceptor is an essential enzyme for
Mtb
cell wall synthesis. Analysis of drug r...

Alternative Titles

Full title

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e87abd4dde1941e494b09a4999a769d0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e87abd4dde1941e494b09a4999a769d0

Other Identifiers

ISSN

1674-800X

E-ISSN

1674-8018

DOI

10.1007/s13238-020-00726-6

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