Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is...
Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells
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Author / Creator
Marchiori, Chiara , Scarpa, Melania , Kotsafti, Andromachi , Morgan, Susan , Fassan, Matteo , Guzzardo, Vincenza , Porzionato, Andrea , Angriman, Imerio , Ruffolo, Cesare , Sut, Stefania , Dall’Acqua, Stefano , Bardini, Romeo , De Caro, Raffaele , Castoro, Carlo , Scarpa, Marco and Castagliuolo, Ignazio
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
One of the most potent costimulatory molecules involved in the recognition and killing of tumor cells is CD80. However, its role and the molecular mechanisms regulating its expression in sporadic colorectal carcinogenesis remain elusive. Here, we provide evidence for CD80 overexpression in human colon epithelial cells derived from preneoplastic muc...
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Full title
Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e89f4450d6954c29a710e99a9d9aad08
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e89f4450d6954c29a710e99a9d9aad08
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-019-1205-0
