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Development of a drug screening system using three-dimensional cardiac tissues containing multiple c...

Development of a drug screening system using three-dimensional cardiac tissues containing multiple c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8d088719a1542128974b40335af742f

Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types

About this item

Full title

Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-03, Vol.11 (1), p.5654-5654, Article 5654

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We hypothesized that an appropriate ratio of cardiomyocytes, fibroblasts, endothelial cells, and extracellular matrix (ECM) factors would be required for the development of three-dimensional cardiac tissues (3D-CTs) as drug screening systems. To verify this hypothesis, ECM-coated human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs...

Alternative Titles

Full title

Development of a drug screening system using three-dimensional cardiac tissues containing multiple cell types

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e8d088719a1542128974b40335af742f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8d088719a1542128974b40335af742f

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-85261-y

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