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The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-...

The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8dfc52f0e2d4bf0ad4919b7953cc41c

The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

About this item

Full title

The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Publisher

Switzerland: MDPI

Journal title

Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.666

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Autophagy is an important innate immune defense mechanism that controls Mycobacterium tuberculosis (Mtb) growth inside macrophages. Autophagy machinery targets Mtb-containing phagosomes via xenophagy after damage to the phagosomal membrane due to the Type VII secretion system Esx-1 or via LC3-associated phagocytosis without phagosomal damage. Conve...

Alternative Titles

Full title

The Lipid Virulence Factors of Mycobacterium tuberculosis Exert Multilayered Control over Autophagy-Related Pathways in Infected Human Macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e8dfc52f0e2d4bf0ad4919b7953cc41c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8dfc52f0e2d4bf0ad4919b7953cc41c

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells9030666

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