FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and d...
FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Alterations towards a permissive stromal microenvironment provide important cues for tumor growth, invasion, and metastasis. In this study, Fibroblast activation protein (FAP), a serine protease selectively produced by tumor-associated fibroblasts in over 90% of epithelial tumors, was used as a platform for studying tumor-stromal interactions. We t...
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Full title
FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells
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TN_cdi_doaj_primary_oai_doaj_org_article_e8f363b199c946d6b0aad2fe3b5d6a28
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8f363b199c946d6b0aad2fe3b5d6a28
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-11-245
