Dynamics of antigen presentation to transgene product-specific CD4 + T cells and of Treg induction u...
Dynamics of antigen presentation to transgene product-specific CD4 + T cells and of Treg induction upon hepatic AAV gene transfer
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Publisher
United States: Elsevier Limited
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Language
English
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United States: Elsevier Limited
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The tolerogenic hepatic microenvironment impedes clearance of viral infections but is an advantage in viral vector gene transfer, which often results in immune tolerance induction to transgene products. Although the underlying tolerance mechanism has been extensively studied, our understanding of antigen presentation to transgene product-specific C...
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Full title
Dynamics of antigen presentation to transgene product-specific CD4 + T cells and of Treg induction upon hepatic AAV gene transfer
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TN_cdi_doaj_primary_oai_doaj_org_article_e8fcc8b2b0814e77b149f37b5fbe352e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e8fcc8b2b0814e77b149f37b5fbe352e
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ISSN
2329-0501
E-ISSN
2329-0501
DOI
10.1038/mtm.2016.83
