Roles of neuropathology-associated reactive astrocytes: a systematic review
Roles of neuropathology-associated reactive astrocytes: a systematic review
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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In the contexts of aging, injury, or neuroinflammation, activated microglia signaling with TNF-α, IL-1α, and C1q induces a neurotoxic astrocytic phenotype, classified as A1, A1-like, or neuroinflammatory reactive astrocytes. In contrast to typical astrocytes, which promote neuronal survival, support synapses, and maintain blood–brain barrier integr...
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Full title
Roles of neuropathology-associated reactive astrocytes: a systematic review
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TN_cdi_doaj_primary_oai_doaj_org_article_e90a6d5dabcd4ca2bf15e2f68d526558
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e90a6d5dabcd4ca2bf15e2f68d526558
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-023-01526-9
