Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory recepto...
Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
About this item
Full title
Author / Creator
Bashkirova, Elizaveta V , Klimpert, Nell , Monahan, Kevin , Campbell, Christine E , Osinski, Jason , Tan, Longzhi , Schieren, Ira , Pourmorady, Ariel , Stecky, Beka , Barnea, Gilad , Xie, Xiaoliang Sunney , Abdus-Saboor, Ishmail , Shykind, Benjamin M , Marlin, Bianca J , Gronostajski, Richard M , Fleischmann, Alexander and Lomvardas, Stavros
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
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Publication information
Publisher
England: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Olfactory receptor (OR) choice represents an example of genetically hardwired stochasticity, where every olfactory neuron expresses one out of ~2000 OR alleles in the mouse genome in a probabilistic, yet stereotypic fashion. Here, we propose that topographic restrictions in OR expression are established in neuronal progenitors by two opposing force...
Alternative Titles
Full title
Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice
Authors, Artists and Contributors
Author / Creator
Klimpert, Nell
Monahan, Kevin
Campbell, Christine E
Osinski, Jason
Tan, Longzhi
Schieren, Ira
Pourmorady, Ariel
Stecky, Beka
Barnea, Gilad
Xie, Xiaoliang Sunney
Abdus-Saboor, Ishmail
Shykind, Benjamin M
Marlin, Bianca J
Gronostajski, Richard M
Fleischmann, Alexander
Lomvardas, Stavros
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e923cd877d264e7291581c56826388d1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e923cd877d264e7291581c56826388d1
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.87445
