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Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e933d62fb57a4584bbb48addf8ffc84e

Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

About this item

Full title

Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2016-05, Vol.5

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The ability to detect and/or manipulate specific cell populations based upon the presence of intracellular protein epitopes would enable many types of studies and applications. Protein binders such as nanobodies (Nbs) can target untagged proteins (antigens) in the intracellular environment. However, genetically expressed protein binders are stable...

Alternative Titles

Full title

Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e933d62fb57a4584bbb48addf8ffc84e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e933d62fb57a4584bbb48addf8ffc84e

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.15312

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