CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes
CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes
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Author / Creator
Elkjaer, Maria L. , Nawrocki, Arkadiusz , Kacprowski, Tim , Lassen, Pernille , Simonsen, Anja Hviid , Marignier, Romain , Sejbaek, Tobias , Nielsen, Helle H. , Wermuth, Lene , Rashid, Alyaa Yakut , Høgh, Peter , Sellebjerg, Finn , Reynolds, Richard , Baumbach, Jan , Larsen, Martin R. and Illes, Zsolt
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
To identify markers in the CSF of multiple sclerosis (MS) subtypes, we used a two-step proteomic approach: (i) Discovery proteomics compared 169 pooled CSF from MS subtypes and inflammatory/degenerative CNS diseases (NMO spectrum and Alzheimer disease) and healthy controls. (ii) Next, 299 proteins selected by comprehensive statistics were quantifie...
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Full title
CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes
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TN_cdi_doaj_primary_oai_doaj_org_article_e937c16553044bfc90da330ef33a440f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e937c16553044bfc90da330ef33a440f
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-83591-5