Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity
Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
The comprehensive assessment of long-term effects of reducing intake of energy (CALERIE-II; NCT00427193) clinical trial established that caloric restriction (CR) in humans lowers inflammation. The identity and mechanism of endogenous CR-mimetics that can be deployed to control obesity-associated inflammation and diseases are not well understood. Ou...
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Full title
Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity
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TN_cdi_doaj_primary_oai_doaj_org_article_e954530dc5224073ad8d80f78f968471
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e954530dc5224073ad8d80f78f968471
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI169173
