A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease
A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease
About this item
Full title
Author / Creator
SCarlet RoAD Investigators , for the SCarlet RoAD Investigators , Sahlgrenska akademin , Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi , Göteborgs universitet , Gothenburg University , Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry , Sahlgrenska Academy , Ostrowitzki, Susanne , Lasser, Robert A , Dorflinger, Ernest , Scheltens, Philip , Barkhof, Frederik , Nikolcheva, Tania , Ashford, Elizabeth , Retout, Sylvie , Hofmann, Carsten , Delmar, Paul , Klein, Gregory , Andjelkovic, Mirjana , Dubois, Bruno , Boada, Mercè , Blennow, Kaj , Santarelli, Luca and Fontoura, Paulo
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Gantenerumab is a fully human monoclonal antibody that binds aggregated amyloid-β (Aβ) and removes Aβ plaques by Fc receptor-mediated phagocytosis. In the SCarlet RoAD trial, we assessed the efficacy and safety of gantenerumab in prodromal Alzheimer's disease (AD).
In this randomized, double-blind, placebo-controlled phase III study, we investig...
Alternative Titles
Full title
A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
for the SCarlet RoAD Investigators
Sahlgrenska akademin
Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi
Göteborgs universitet
Gothenburg University
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Sahlgrenska Academy
Ostrowitzki, Susanne
Lasser, Robert A
Dorflinger, Ernest
Scheltens, Philip
Barkhof, Frederik
Nikolcheva, Tania
Ashford, Elizabeth
Retout, Sylvie
Hofmann, Carsten
Delmar, Paul
Klein, Gregory
Andjelkovic, Mirjana
Dubois, Bruno
Boada, Mercè
Blennow, Kaj
Santarelli, Luca
Fontoura, Paulo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_e955ede30f6c4f9ea14e0090bdf6615d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e955ede30f6c4f9ea14e0090bdf6615d
Other Identifiers
ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-017-0318-y
