Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibi...
Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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There is an unmet need for antifibrotic therapies to prevent the progression of liver cirrhosis. Previously, we conducted an exploratory trial to assess the safety and antifibrotic efficacy of PRI-724, a selective CBP/β-catenin inhibitor, in patients with liver cirrhosis. PRI-724 was well tolerated and exerted a potential antifibrotic effect. Here,...
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Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis
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TN_cdi_doaj_primary_oai_doaj_org_article_e973a4feb8e641d6a1cfb726a0e430a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e973a4feb8e641d6a1cfb726a0e430a8
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-56942-1
