Degradation of methylation signals in cryopreserved DNA
Degradation of methylation signals in cryopreserved DNA
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Blood-based DNA methylation has shown great promise as a biomarker in a wide variety of diseases. Studies of DNA methylation in blood often utilize samples which have been cryopreserved for years or even decades. Therefore, changes in DNA methylation associated with long-term cryopreservation can introduce biases or otherwise mislead met...
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Degradation of methylation signals in cryopreserved DNA
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TN_cdi_doaj_primary_oai_doaj_org_article_e9954d81753d423bb5f23e820cd2fa2d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e9954d81753d423bb5f23e820cd2fa2d
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ISSN
1868-7083,1868-7075
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-023-01565-y