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Degradation of methylation signals in cryopreserved DNA

Degradation of methylation signals in cryopreserved DNA

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e9954d81753d423bb5f23e820cd2fa2d

Degradation of methylation signals in cryopreserved DNA

About this item

Full title

Degradation of methylation signals in cryopreserved DNA

Publisher

London: BioMed Central Ltd

Journal title

Clinical epigenetics, 2023-09, Vol.15 (1), p.1-10, Article 147

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background Blood-based DNA methylation has shown great promise as a biomarker in a wide variety of diseases. Studies of DNA methylation in blood often utilize samples which have been cryopreserved for years or even decades. Therefore, changes in DNA methylation associated with long-term cryopreservation can introduce biases or otherwise mislead met...

Alternative Titles

Full title

Degradation of methylation signals in cryopreserved DNA

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_e9954d81753d423bb5f23e820cd2fa2d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e9954d81753d423bb5f23e820cd2fa2d

Other Identifiers

ISSN

1868-7083,1868-7075

E-ISSN

1868-7083,1868-7075

DOI

10.1186/s13148-023-01565-y

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