Covalent Affibody‐Molecular Glue Drug Conjugate Nanoagent for Proximity‐Enabled Reactive Therapeutic...
Covalent Affibody‐Molecular Glue Drug Conjugate Nanoagent for Proximity‐Enabled Reactive Therapeutics
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Publisher
Germany: John Wiley & Sons, Inc
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Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Contents
Sulfur‐fluoride exchange (SuFEx) reaction is an emerging class of click chemistry reaction. Owing to its efficient reactivity under physiological conditions, SuFEx reaction is used to construct covalent protein drugs. Herein, a covalent affibody‐molecular glue drug conjugate nanoagent is reported, which can irreversibly bind with its target protein...
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Full title
Covalent Affibody‐Molecular Glue Drug Conjugate Nanoagent for Proximity‐Enabled Reactive Therapeutics
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TN_cdi_doaj_primary_oai_doaj_org_article_e9b48f3377e84ca1a4a9382dc1a47d45
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_e9b48f3377e84ca1a4a9382dc1a47d45
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ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202412273
