Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor sp...
Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Contents
The T cell receptor (TCR) repertoire encodes immune exposure history through the dynamic formation of immunological memory. Statistical analysis of repertoire sequencing data has the potential to decode disease associations from large cohorts with measured phenotypes. However, the repertoire perturbation induced by a given immunological challenge i...
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Full title
Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity
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TN_cdi_doaj_primary_oai_doaj_org_article_ea01accb19154c68820bffc0cb1efcbb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea01accb19154c68820bffc0cb1efcbb
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.38358