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Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor sp...

Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor sp...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea01accb19154c68820bffc0cb1efcbb

Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

About this item

Full title

Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2018-08, Vol.7

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

The T cell receptor (TCR) repertoire encodes immune exposure history through the dynamic formation of immunological memory. Statistical analysis of repertoire sequencing data has the potential to decode disease associations from large cohorts with measured phenotypes. However, the repertoire perturbation induced by a given immunological challenge i...

Alternative Titles

Full title

Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ea01accb19154c68820bffc0cb1efcbb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea01accb19154c68820bffc0cb1efcbb

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.38358

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