Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils
Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Myeloid lineage cells suppress T cell viability through arginine depletion via arginase 1 (ARG1). Despite numerous studies exploring the mechanisms by which ARG1 perturbs lymphocyte function, the cellular populations responsible for its generation and release remain poorly understood. Here, we showed that neutrophil lineage cells and not monocytes...
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Full title
Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ea22b9ea0f034276943aff6b41b27330
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea22b9ea0f034276943aff6b41b27330
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI153643
